Regional Conference on Computer and Information Engineering (RC-CIE) 2015 was conducted at Hanoi, capital of Vietname. The conference was hosted by Hanoi University of Science and Technology (HUST) and Asean University Network / South East Asia Engineering Education Development Network to promote active research collaboration in Computer and Information Engineering field. The conference was held on 1 – 2 October 2015 at the Ta Quang Buu Library building, HUST. The program committee selected 29 research papers out of 52 invited research papers to be presented in front of delegations from member institutions and japanese supporting universities. The scientific meeting was closed with a concluded development program for 2016 and a fruitful farewell party.